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Article

Suppression of UV-induced mutations by wild-type p53 protein in human osteosarcoma cells.

Mutagenesis - 1 May 1997

Yamagishi N, Miyakoshi J, Yagi T, Takebe H

Abstract excerpt

We have examined whether the tumour suppressor p53 protein suppressed UV-induced mutations in the hypoxathine-guanine phosphoribosyl transferase (HPRT) gene and in the supF gene of the shuttle vector plasmid pMY189. We used human osteosarcoma Saos-LP12 cells, in which wild type (wt) p53 protein was induced by treatment with isopopyl-beta-D-thiogalactopyranoside. The induction of wt p53 protein suppressed...

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Identifiers

PMID: 9175647
DOI: 10.1093/mutage/12.3.191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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