Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular markers for malignancy in adrenocortical tumors.

Hormone research - 1 Jan 1997

Gicquel C, Le Bouc Y

Abstract excerpt

Little is known about the pathophysiology of sporadic adrenocortical tumors. Benign and malignant adrenocortical tumors are often difficult to distinguish by conventional histology. We tested 38 adrenocortical tumors (23 benign and 15 malignant) for loss of heterozygosity (LOH) at 17p13 and abnormalities in the 11p15 region (uniparental disomy, UPD, and overexpression of the IGF II gene). We showed that 17p13...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to Chromosomes, Human, Pair 17

Share to Gene Expression

Share to Heterozygote

Share to RNA, Messenger

Source

Identifiers

PMID: 9167963
DOI: 10.1159/000185475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular markers for malignancy in adrenocortical tumors.PMID 9167963Read ↗

Structural and functional abnormalities at 11p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: study on a series of 82 tumors.Semantic proximity Read ↗

Rearrangements at the 11p15 locus and overexpression of insulin-like growth factor-II gene in sporadic adrenocortical tumors.Semantic proximity Read ↗

Somatic TP53 mutations are relatively rare among adrenocortical cancers with the frequent 17p13 loss of heterozygosity.Semantic proximity Read ↗

Pathogenesis of adrenocortical incidentalomas and genetic syndromes associated with adrenocortical neoplasms.Semantic proximity Read ↗

A Case Report in Favor of a Multistep Adrenocortical TumorigenesisSemantic proximity Read ↗

[Involvement of the IGF system in the pathogenesis of adrenocortical tumors].Semantic proximity Read ↗

Two distinct tumor suppressor loci within chromosome 11p15 implicated in breast cancer progression and metastasis.Semantic proximity Read ↗

Increased expression of the insulin-like growth factor-II gene in Wilms' tumor is not dependent on loss of genomic imprinting or loss of heterozygosity.Semantic proximity Read ↗

IGF2 promotes growth of adrenocortical carcinoma cells, but its overexpression does not modify phenotypic and molecular features of adrenocortical carcinoma.Semantic proximity Read ↗

Insulin-like growth factor system on adrenocortical tumorigenesisSemantic proximity Read ↗

Pediatric Adrenocortical Tumors: Molecular Events Leading to Insulin-Like Growth Factor II Gene Overexpression*Semantic proximity Read ↗

Genotyping of adrenocortical tumors: very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.