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Article

A Case Report in Favor of a Multistep Adrenocortical Tumorigenesis

1 Mar 2003

Abstract excerpt

The mechanisms of adrenocortical tumorigenesis are still not fully understood. Data from clonal analysis, comparative genomic hybridization, and allelotyping suggest that it involves a multistep process during which several genetic defects are progressively acquired, leading to the malignant transformation. The events involved in the first steps of this process are not well known, and most of the abnormalities...

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PMID: 12629075
DOI: 10.1210/jc.2002-021117

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