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Article

Two distinct tumor suppressor loci within chromosome 11p15 implicated in breast cancer progression and metastasis.

Human molecular genetics - 1 May 1998

Karnik P, Paris M, Williams B R, Casey G, Crowe J, Chen P

Abstract excerpt

Chromosome 11p15 has attracted considerable attention because of the biological importance of this region to human disease. Apart from being an important tumor suppressor locus showing loss of heterozygosity (LOH) in several adult and childhood cancers, 11p15 has been shown by linkage analysis to harbor the gene(s) for the Beckwith-Wiedemann syndrome. Furthermore, the clustering of known imprinted genes in the...

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Identifiers

PMID: 9536095
DOI: 10.1093/hmg/7.5.895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two distinct tumor suppressor loci within chromosome 11p15 implicated in breast cancer progression and metastasis.PMID 9536095Read ↗

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