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Article

CYP2D6-related oxidation polymorphism in a Canadian Inuit population.

Canadian journal of physiology and pharmacology - 1 Mar 1997

Jurima-Romet M, Foster B C, Casley W L, Rode A, Vloshinsky P, Huang H S, Geertsen S

Abstract excerpt

The xenobiotic oxidation polymorphism associated with cytochrome P450 2D6 (CYP2D6) was investigated in 152 genetically related and unrelated healthy Inuit subjects living in the High Arctic of eastern Canada. Phenotyping was based on HPLC determination of the CYP2D6-related dextromethorphan metabolic ratio in overnight urine samples after oral administration of 30 mg dextromethorphan hydrobromide. The log...

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PMID: 9164697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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