Article
Genetic polymorphism of CYP2D6 in North Indian subjects.
European journal of clinical pharmacology - 1 Jan 2000
Lamba V, Lamba J K, Dilawari J B, Kohli K K
Abstract excerpt
OBJECTIVES: CYP2D6 polymorphism of clinical relevance occurs with variable frequency in different ethnic groups. Since this polymorphism has not been studied in a North Indian population, the present study was undertaken. METHODS: One hundred healthy unrelated North Indian subjects received 30 mg...
Topics
- Adolescent
- Adult
- Antitussive Agents
- Biotransformation
- Chromatography, High Pressure Liquid
- Cytochrome P-450 CYP2D6
- Dextromethorphan
- Female
- Gene Frequency
- Humans
- Indians, North American
- Male
- Middle Aged
- Phenotype
- Polymorphism, Genetic
