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Article

Genetic polymorphism of CYP2D6 in Karnataka and Andhra Pradesh population in India.

Acta pharmacologica Sinica - 1 Jun 2000

Abraham B K, Adithan C, Kiran P U, Asad M, Koumaravelou K

Abstract excerpt

AIM: To study the prevalence of cytochrome P-450 2D6 (CYP2D6) polymorphism in Karnataka (KA) and Andhra Pradesh (AP) population. METHODS: Two hundred and eleven healthy human volunteers participated in the study (100 from KA and 111 from AP). At bed time, after voiding their bladder, the volunteers ingested 30 mg of dextromethorphan hydrobromide (DM). Urine samples were collected for 8 h. DM and its metabolite...

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PMID: 11360682

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