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Article

Hypofibrinolytic State in Subjects with Type 2 Diabetes Mellitus Aggravated by the Metabolic Syndrome before Clinical Manifestations of Atherothrombotic Disease.

BioMed research international - 1 Jan 2017

Aburto-Mejía Elsa, Santiago-Germán David, Martínez-Marino Manuel, María Eugenia Galván-Plata, Almeida-Gutiérrez Eduardo, López-Alarcón Mardia, Hernández-Juárez Jesús, Alvarado-Moreno Antonio, Leaños-Miranda Alfredo, Majluf-Cruz Abraham, Isordia-Salas Irma

Abstract excerpt

Background. Metabolic and genetic factors induce plasminogen activator inhibitor type-1 (PAI-1) overexpression; higher PAI-1 levels decrease fibrinolysis and promote atherothrombosis. Aim. To assess PAI-1 antigen levels among subjects with type 2 diabetes mellitus (T2DM) plus Metabolic Syndrome (MetS) before clinical manifestations of atherothrombosis and the contribution of metabolic factors and 4G/5G...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28271069
DOI: 10.1155/2017/6519704
PMCID: PMC5320378

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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