Article
Environmental and genetic factors in relation to elevated circulating levels of plasminogen activator inhibitor-1 in Caucasian patients with non-insulin-dependent diabetes mellitus.
Thrombosis and haemostasis - 1 Sept 1995
Mansfield M W, Stickland M H, Grant P J
Abstract excerpt
To investigate the interaction of metabolic and genetic factors in relation to PAI-1, genotype was determined at a 4G/5G polymorphism in the PAI-1 gene promoter and a Hind III RFLP of the PAI-1 gene in 189 Caucasian NIDDM patients. PAI-1 levels were equivalent in each genotype group and PAI-1 act...
Topics
- Adult
- Aged
- Analysis of Variance
- Base Sequence
- Chromosome Mapping
- Diabetes Mellitus, Type 2
- Environmental Health
- Female
- Genetic Variation
- Genotype
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Plasminogen Activator Inhibitor 1
- Polymorphism, Genetic
- White People