Article
Study of NAT2 genetic polymorphism in West African subjects: example of an healthy non-smoker Senegalese population.
Molecular biology reports - 1 Dec 2012
Touré A, Diop C, Cabral M, Fall M, Lhermitte M, Diouf A, Broly F, Allorge D
Abstract excerpt
The NAT2 genetic polymorphism determines the individual acetylator status and, consequently, the capacity to metabolize, or not, drugs and xenobiotics which are substrates of NAT2. As the nature and frequency of the NAT2 polymorphisms vary remarkably between populations of different ethnic origins, genotyping strategies used to predict the acetylation phenotype need to be adapted for each particular population...
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