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Article

Thymocyte progenitors and T cell development in aging.

Mechanisms of ageing and development - 1 Mar 1997

Yu S, Abel L, Globerson A

Abstract excerpt

Dysfunction of T lymphocytes in aging has been causally related to a gradual loss of the thymic microenvironmental function. However, in view of the fact that T cells are generated from bone marrow-derived stem cells that settle in the thymus, we have investigated the possibility that aging effects on the bone marrow have an impact on T cell development. Our approach was based on seeding of bone marrow cells,...

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Identifiers

PMID: 9147363
DOI: 10.1016/s0047-6374(97)01868-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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