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Article

An Epithelial Progenitor Pool Regulates Thymus Growth

1 Nov 2008

Abstract excerpt

Thymic epithelium provides an essential cellular substrate for T cell development and selection. Gradual age-associated thymic atrophy leads to a reduction in functional thymic tissue and a decline in de novo T cell generation. Development of strategies tailored toward regeneration of thymic tissue provides an important possibility to improve immune function in elderly individuals and increase the capacity for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18941199
DOI: 10.4049/jimmunol.181.9.6101

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