Rat bone marrow cells undergo thymopoiesis in mouse fetal thymic organ culture.

doi:10.1002/eji.1830200928

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Article

Rat bone marrow cells undergo thymopoiesis in mouse fetal thymic organ culture.

European journal of immunology - 1 Sept 1990

Deugnier M A, Dargemont C, Denoyelle M, Blanche M, Imhof B A, Thiery J P

Abstract excerpt

We have developed an in vitro differentiation assay allowing the study of thymopoiesis from rat bone marrow cells. In this assay, Wistar rat bone marrow cells repopulated fetal Swiss mouse thymic lobes depleted in endogeneous lymphoid cells by deoxyguanosine treatment. Due to the xenogeneic situa...

Topics

Animals
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
Bone Marrow
CD8 Antigens
Female
Fetus
Hematopoiesis
Hematopoietic Stem Cells
Male
Mice
Organ Culture Techniques
Phenotype
Rats
Rats, Inbred Strains
Receptors, Antigen, T-Cell
T-Lymphocytes
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 2120073
DOI: 10.1002/eji.1830200928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2120073-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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