Article
Rat bone marrow cells undergo thymopoiesis in mouse fetal thymic organ culture.
European journal of immunology - 1 Sept 1990
Deugnier M A, Dargemont C, Denoyelle M, Blanche M, Imhof B A, Thiery J P
Abstract excerpt
We have developed an in vitro differentiation assay allowing the study of thymopoiesis from rat bone marrow cells. In this assay, Wistar rat bone marrow cells repopulated fetal Swiss mouse thymic lobes depleted in endogeneous lymphoid cells by deoxyguanosine treatment. Due to the xenogeneic situation, repopulating rat cells from any hemopoietic lineage could be easily recognized by anti-rat monoclonal antibodies...
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