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Article

Mutational state of von Hippel-Lindau and adenomatous polyposis coli genes in renal tumors.

Oncology - 1 Jan 2000

Suzuki H, Ueda T, Komiya A, Okano T, Isaka S, Shimazaki J, Ito H

Abstract excerpt

Genetic alterations of the von Hippel-Lindau (VHL) tumor suppressor gene and the adenomatous polyposis coli (APC) gene in renal tumors were examined by PCR-SSCP analysis and direct sequencing. Tissues from 58 primary sporadic human renal cell tumors (49 clear-cell carcinomas, 6 non-clear-cell carcinomas and 3 oncocytomas) from Japanese patients were used in this study. Somatic VHL mutations were detected in 26...

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Source

Identifiers

PMID: 9143408
DOI: 10.1159/000227697

Genes

VHL
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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