Article
Mapping of a major susceptibility locus for Graves' disease (GD-1) to chromosome 14q31.
The Journal of clinical endocrinology and metabolism - 1 May 1997
Tomer Y, Barbesino G, Keddache M, Greenberg D A, Davies T F
Abstract excerpt
The autoimmune thyroid diseases (AITD), encompassing Graves' disease (GD) and Hashimoto's thyroiditis (HT), occur in genetically susceptible individuals. In order to identify the AITD susceptibility genes, we have studied DNA markers in the regions of 8 candidate genes: (1) the HLA region, (2) the TSH receptor, (3) thyroid peroxidase, (4) thyroglobulin, (5) IDDM-4, (6) IDDM-5, (7) Immunoglobulin heavy chain gene...
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