Article
Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function.
Endocrine reviews - 1 Oct 2003
Tomer Yaron, Davies Terry F
Abstract excerpt
The autoimmune thyroid diseases (AITD) are complex diseases that are caused by an interaction between susceptibility genes and environmental triggers. Genetic susceptibility, in combination with external factors (e.g., dietary iodine), is believed to initiate the autoimmune response to thyroid antigens. Abundant epidemiological data, including family and twin studies, point to a strong genetic influence on the...
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