Article
Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families.
American journal of human genetics - 1 Oct 2003
Tomer Yaron, Ban Yoshiyuki, Concepcion Erlinda, Barbesino Giuseppe, Villanueva Ronald, Greenberg David A, Davies Terry F
Abstract excerpt
The autoimmune thyroid diseases (AITDs), comprising Graves disease (GD) and Hashimoto thyroiditis (HT), develop as a result of a complex interaction between predisposing genes and environmental triggers. Previously, we identified six loci that showed evidence for linkage with AITD in a data set of 56 multiplex families. The goals of the present study were to replicate/reject the previously identified loci before...
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