Article
Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes.
The Journal of clinical endocrinology and metabolism - 1 Jan 2013
Tomer Yaron, Hasham Alia, Davies Terry F, Stefan Mihaela, Concepcion Erlinda, Keddache Mehdi, Greenberg David A
Abstract excerpt
CONTEXT: Genetic factors play a major role in the etiology of autoimmune thyroid disease (AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). We have previously identified three loci on chromosomes 10q, 12q, and 14q that showed strong linkage with AITD, HT, and GD, respectively. OBJECTIVES: The objective of the study was to identify the AITD susceptibility genes at the 10q, 12q, and 14q loci....
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