Article
The genetic susceptibility to Graves' disease.
Bailliere's clinical endocrinology and metabolism - 1 Oct 1997
Tomer Y, Davies T F
Abstract excerpt
Graves' disease (GD) develops as a result of a complex interaction between genetic susceptibility genes and likely environmental factors. Most epidemiological data support an important genetic contribution to the development of GD. The concordance rate of GD in monozygotic twins is 30-60% and in dizygotic twins 3-9%, and thyroid autoantibodies have been reported in up to 50% of the siblings of patients with GD....
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