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Article

A molecular, clinical, and immunohistochemical study of vestibular schwannoma.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Apr 1997

Irving R M, Moffat D A, Hardy D G, Barton D E, Xuereb J H, Holland F J, Maher E R

Abstract excerpt

The molecular pathogenesis of vestibular schwannoma has been investigated by determining the extent of chromosome 22 loss of heterozygosity in 77 tumors and relating these findings to clinical and immunohistochemical indexes of tumor behavior. Loss of heterozygosity was looked for at eight chromosome 22q loci. Clinical details were obtained in all 77 cases, and a clinical growth index was calculated for each...

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PMID: 9141389
DOI: 10.1016/S0194-59989770289-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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