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Article

Molecular genetics alterations and tumor behavior of sporadic vestibular schwannoma from the People's Republic of China.

Journal of neuro-oncology - 1 Jul 2005

Bian Liu-Guan, Tirakotai Wuttipong, Sun Qing-Fang, Zhao Wei-Guo, Shen Jian-Kang, Luo Qi-Zhong

Abstract excerpt

OBJECTIVES: To analyze the molecular genetic alteration of sporadic vestibular schwannomas from the People's Republic of China and to correlate these alterations with the tumor behaviors. METHODS: Four highly polymorphic microsatellite DNA markers were used to observe the frequency of loss of heterozygosity (LOH) in chromosome 22. The NF2 gene mutations were detected by Polymerase chain reaction-single-strand...

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Share to Blotting, Western
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Neurofibromatosis 2

Share to Immunohistochemistry

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Share to Neuroma, Acoustic

Share to Polymorphism, Single-Stranded Conformational

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Identifiers

PMID: 15980976
DOI: 10.1007/s11060-004-5176-3

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