Analysis of mutations in the SCH gene in schwannomas.

doi:10.1002/gcc.2870110103

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Article

Analysis of mutations in the SCH gene in schwannomas.

Genes, chromosomes & cancer - 1 Sept 1994

Bijlsma E K, Merel P, Bosch D A, Westerveld A, Delattre O, Thomas G, Hulsebos T J

Abstract excerpt

Schwannomas are benign tumors of cranial, spinal, and other nerve sheaths that develop sporadically or are inherited as part of neurofibromatosis type 2 (NF2). The NF2 gene (SCH) on chromosome 22 has recently been identified and shown to be inactivated by mutation and allele loss in some schwanno...

Topics

Alleles
Base Sequence
Central Nervous System Neoplasms
Chromosomes, Human, Pair 22
Codon
Cranial Nerve Neoplasms
DNA Mutational Analysis
DNA, Neoplasm
Exons
Genes, Neurofibromatosis 2
Humans
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Neoplasm Proteins

Neurilemmoma

Neurofibromatosis 2

Neurofibromin 2

Neuroma, Acoustic

Source

Open in PubMed

Identifiers

PMID: 7529050
DOI: 10.1002/gcc.2870110103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7529050-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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