Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and Epigenetic Alterations of the NF2 Gene in Sporadic Vestibular Schwannomas

25 Jan 2012

Abstract excerpt

BACKGROUND: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identified in not only NF2-related tumors but also sporadic vestibular schwannomas (VS). This study investigated the genetic and epigenetic alterations in tumors and blood from 30 Korean patients with sporadic VS and correlated these alterations with tumor behavior. METHODOLOGY/PRINCIPAL FINDINGS: NF2 gene mutations were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Meningioma and schwannoma management
Share to Neurofibromatosis and Schwannoma Cases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22295085
DOI: 10.1371/journal.pone.0030418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and Epigenetic Alterations of the NF2 Gene in Sporadic Vestibular SchwannomasPMID 22295085Read ↗

Molecular genetics alterations and tumor behavior of sporadic vestibular schwannoma from the People's Republic of China.Semantic proximity Read ↗

NF2 Genetic Alterations in Sporadic Vestibular SchwannomasSemantic proximity Read ↗

Lack of neurofibromatosis type 2 gene promoter methylation in sporadic vestibular schwannomas.Semantic proximity Read ↗

Genetic landscape of sporadic vestibular schwannoma.Semantic proximity Read ↗

Next Generation Sequencing of Sporadic Vestibular Schwannoma: Necessity of Biallelic NF2 Inactivation and Implications of Accessory Non-NF2 Variants.Semantic proximity Read ↗

Genomics, Epigenetics, and Hearing Loss in Neurofibromatosis Type 2Semantic proximity Read ↗

Molecular biology of familial and sporadic vestibular schwannomas: implications for novel therapeutics.Semantic proximity Read ↗

Clinical manifestations of mutations in the neurofibromatosis type 2 gene in vestibular schwannomas (acoustic neuromas).Semantic proximity Read ↗

Pathogenic Variants and Allele Loss of the NF2 and LZTR1 Gene in Sporadic Vestibular SchwannomaSemantic proximity Read ↗

Familial schwannomatosisSemantic proximity Read ↗

Genetic Analysis of Intracranial Schwannomas: Differential NF2 Alteration Frequencies in Nonvestibular Schwannomas Versus Vestibular SchwannomasSemantic proximity Read ↗

CpG island hypermethylation of the neurofibromatosis type 2 (NF2) gene is rare in sporadic vestibular schwannomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.