Article
RNA-dependent association of the Drosophila maleless protein with the male X chromosome.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Mar 1996
Richter L, Bone J R, Kuroda M I
Abstract excerpt
BACKGROUND: Dosage compensation results in equivalent X-linked gene expression in males (XY) and females (XX). In Drosophila, both X chromosomes are active in females, and the single male X must double its transcriptional activity to allow male development. Four proteins (encoded by the male-specific lethal genes) are required for dosage compensation and associate with the X chromosome in males but not in...
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