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Article

The Drosophila GAGA factor is required for dosage compensation in males and for the formation of the male-specific-lethal complex chromatin entry site at 12DE.

Genetics - 1 Jan 2004

Greenberg Anthony J, Yanowitz Judith L, Schedl Paul

Abstract excerpt

Drosophila melanogaster males have one X chromosome, while females have two. To compensate for the resulting disparity in X-linked gene expression between the two sexes, most genes from the male X chromosome are hyperactivated by a special dosage compensation system. Dosage compensation is achieved by a complex of at least six proteins and two noncoding RNAs that specifically associate with the male X. A central...

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Identifiers

PMID: 15020425
DOI: 10.1534/genetics.166.1.279
PMCID: PMC1470682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The Drosophila GAGA factor is required for dosage compensation in males and for the formation of the male-specific-lethal complex chromatin entry site at 12DE.PMID 15020425Read ↗

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X chromosome sites autonomously recruit the dosage compensation complex in Drosophila males.Semantic proximity Read ↗

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