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Article

Drosophila maleless gene counteracts X global aneuploid effects in males.

The FEBS journal - 1 Sept 2016

Bhadra Utpal, Gandhi Sumit G, Palaparthi Ramesh, Balyan Manoj K, Pal-Bhadra Manika

Abstract excerpt

UNLABELLED: The loss of the entire X chromosome in Drosophila males generates a genome-wide aneuploid effect. We have employed a systems biology approach (microarray) to investigate the global aneuploid effect of the maleless (mle) mutation that disrupts the binding of male specific lethal (MSL) proteins that function in dosage compensation. A large number of the genes (144) that encode a broad spectrum of...

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Share to Aneuploidy
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Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dosage Compensation, Genetic

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Source

Identifiers

PMID: 27456781
DOI: 10.1111/febs.13818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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