Article
Comparative study of poliovirus excretion after vaccination of infants with two oral polio vaccines prepared on Vero cells or on primary monkey kidney cells.
Journal of medical virology - 1 May 1997
Mallet L, Pelloquin F, Brigaud M, Caudrelier P, Bandet R, Xueref C, Fuchs F, Gibelin N, Goldman C, Moulin J C, de Fraipont F, Montagnon B, Peyron L, Aymard M
Abstract excerpt
A comparative study was designed to assess the bioequivalence of 2 oral poliovaccines (OPV) produced on 2 different cell systems: primary monkey kidney (PMK) cells and the Vero cell line. The Vero cell line has been used to overcome the problem of obtaining a regular supply of high quality monkeys that are devoid of latent viruses. For this study, 9 children were vaccinated with PMK-OPV and 12 children with...
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