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Article

Determinants of monovalent oral polio vaccine mutagenesis in vaccinated elderly people.

Vaccine - 11 Jun 2007

Boot Hein J, Sonsma Jan, van Nunen Femke, Abbink Frithjofna, Kimman Tjeerd G, Buisman Anne-Marie

Abstract excerpt

Live oral poliovirus vaccine (OPV) strains can mutate and recombine during replication in the host. Trivalent OPV has long been used to restrain wild-type poliovirus in developing countries. However, recently WHO advocates using monovalent OPV (mOPV) to finally eradicate poliovirus world-wide. We analysed polioviruses recovered from the faeces of 101 elderly patients (divided into three groups by immune status)...

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Identifiers

PMID: 17482726
DOI: 10.1016/j.vaccine.2007.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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