Article
The recovery of a B2 insertion in the lacI gene of a rat cell line containing a lambda/LIZ shuttle vector.
Mutation research - 14 Apr 1997
de Boer J G, Suri A, Walsh D, Glickman B W
Abstract excerpt
The bacterial lacI gene is in use as a reporter gene for mutation in transgenic mice, rats and in cell lines. During a mutagenesis study in which we used such a rat cell line, we recovered a mutant which features an insertion of a rat B2 repeated sequence element. This sequence element was inserted between positions 77 and 78 in the lacI gene. When the inserted sequence was compared to the published rat B2...
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