DNA sequence analysis of spontaneous mutations at a LacZ transgene integrated on the mouse X chromosome.

doi:10.1093/mutage/8.3.243

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Article

DNA sequence analysis of spontaneous mutations at a LacZ transgene integrated on the mouse X chromosome.

Mutagenesis - 1 May 1993

Gossen J A, de Leeuw W J, Bakker A Q, Vijg J

Abstract excerpt

Transgenic mice with integrated shuttle vectors containing the LacZ mutational target gene were used to study spontaneous mutational events in vivo. The transgenic mouse strain used carries the LacZ transgene on the X chromosome and was previously found to be characterized by approximately 25-fol...

Topics

Animals
Base Sequence
Brain
DNA
DNA, Bacterial
Female
Genes, Bacterial
Genetic Vectors
Liver
Male
Mice
Mice, Inbred Strains
Mice, Transgenic
Molecular Sequence Data
Mutation
X Chromosome
beta-Galactosidase

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