Article
On the origin of unusual mutations recovered from the lacI transgenic assay.
Mutation research - 20 Apr 2003
de Boer Johan G
Abstract excerpt
Amongst approximately 25,000 mutants recovered from tissues of the lacI mouse and rat transgenic mutation assay, we identified seven mutants that carry changes that are unlike the majority of mutations that are normally recovered in these systems. The recovered mutants feature replacements and insertions of sequences that originate in the animal's genome, in the bacteriophage lambda construct that harbors the...
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