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Article

[Experimental study of use of shuttle vector to develop a system of detecting mutagenesis in mammalian cells].

Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao - 1 Mar 1992

Lin F, Fu J, Zhai C

Abstract excerpt

UNLABELLED: The paper presents a series of experimental studies of the use of shuttle vector to develop a short-time mutagenesis system of detecting gene mutation in the mammalian cell at DNA level. The system is based on the finding that in the EB virus the shuttle vector pMCi5 carries LacI gene. The LacI is used as a target of induced mutagenesis in mouse cells. Use pMCi5 plasmid to transform the 3T3 mouse...

Topics

3T3 Cells
Animals
Cells, Cultured
Ethyl Methanesulfonate
Genetic Vectors
Herpesvirus 4, Human
Mice
Mutagenicity Tests
Mutation
Plasmids
Transformation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1328027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1328027-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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