Article
Two-step model for the risk of fatal and incidental lung tumors in rats exposed to radon.
Radiation research - 1 Feb 1999
Heidenreich W F, Jacob P, Paretzke H G, Cross F T, Dagle G E
Abstract excerpt
Data from 4276 rats with radon exposures up to 10,000 WLM at rates up to 1000 WL are analyzed with a two-step clonal expansion model. The age dependences of the hazard for the risks for fatal and for incidental tumors are very different. Therefore, two different parameterizations of the model are...
Topics
- Age Factors
- Animals
- Dose-Response Relationship, Radiation
- Lung Neoplasms
- Models, Biological
- Mutation
- Neoplasms, Radiation-Induced
- Predictive Value of Tests
- Radon
- Rats
- Risk Factors
