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Article

DNA double-strand break repair activities in mammary epithelial cells--influence of endogenous p53 variants.

Carcinogenesis - 1 Jul 2009

Keimling Marlen, Wiesmüller Lisa

Abstract excerpt

Intriguingly, all 10 breast cancer susceptibility genes known today are directly or indirectly related to DNA double-strand break (DSB) repair suggesting a critical role of DSB repair dysfunction in the etiology of this tumor entity. We and others had previously provided evidence indicating that the breast cancer susceptibility gene product p53 controls DSB repair. Experiments with ectopically expressed proteins...

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Share to DNA Breaks, Double-Stranded
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Recombination, Genetic

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Source

Identifiers

PMID: 19429664
DOI: 10.1093/carcin/bgp117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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