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Article

Sickness behavior in mice deficient in interleukin-6 during turpentine abscess and influenza pneumonitis.

The American journal of physiology - 1 Feb 1997

Kozak W, Poli V, Soszynski D, Conn C A, Leon L R, Kluger M J

Abstract excerpt

Interleukin-6 (IL-6), among other cytokines, is thought to be involved in the regulation of sickness behavior (e.g., anorexia, cachexia, fever, and lethargy) induced by infections bacterial and viral origin) and sterile tissue necrosis (burns and surgical traumas). Mice deficient in IL-6 (IL-6 KO) were generated by gene targeting. Homozygous IL-6 KO male and female mice and their appropriate controls were...

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Source

Identifiers

PMID: 9124487
DOI: 10.1152/ajpregu.1997.272.2.R621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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