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Article

Protective role of interleukin-6 in coagulatory and hemostatic disturbance induced by lipopolysaccharide in mice.

Thrombosis and haemostasis - 1 Jun 2004

Inoue Ken-ichiro, Takano Hirohisa, Yanagisawa Rie, Sakurai Miho, Shimada Akinori, Morita Takehito, Sato Masahiko, Yoshino Shin, Yoshikawa Toshikazu, Tohyama Chiharu

Abstract excerpt

Although the role of interleukin (IL)-6 in inflammatory diseases has been previously examined, its role in hemostasis, fibrinolysis, and coagulation during inflammation remains to be established. The present study elucidated the role of IL-6 in hemostatic and coagulatory changes during severe inflammation induced by intraperitoneal administration of lipopolysaccharide (LPS: 1 mg/kg) using IL-6 null (-/-) mice....

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Identifiers

PMID: 15175807
DOI: 10.1160/TH03-09-0595

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MIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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