Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas.

doi:10.1002/(SICI)1096-9896(199702)181:2<178::AID-PATH741>3.0.CO;2-5

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Article

Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas.

The Journal of pathology - 1 Feb 1997

Marchetti A, Buttitta F, Pellegrini S, Bertacca G, Chella A, Carnicelli V, Tognoni V, Filardo A, Angeletti C A, Bevilacqua G

Abstract excerpt

The status of the P16 gene was investigated by Southern blot, polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP), and DNA sequencing analyses in 30 primary resected non-small cell lung carcinomas (NSCLCs) with metastatic involvement of thoracic lymph nodes and 33 NSCLC...

Topics

Adult
Aged
Blotting, Southern
Carcinoma, Non-Small-Cell Lung
Carrier Proteins
Cyclin-Dependent Kinase Inhibitor p16
Genes, Tumor Suppressor
Genes, p53
Humans
Lung Neoplasms
Lymphatic Metastasis
Middle Aged
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 9120722
DOI: 10.1002/(SICI)1096-9896(199702)181:2<178::AID-PATH741>3.0.CO;2-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9120722-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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