Article
Alterations of the p16/MTS1-tumor suppressor gene in gastric cancer.
Pathology, research and practice - 1 Jan 1998
Günther T, Schneider-Stock R, Pross M, Manger T, Malfertheiner P, Lippert H, Roessner A
Abstract excerpt
Deletions, mutations and the functional inactivation of tumor suppressor gene p16 are involved in the genesis of different neoplasias. Little is known about the role of p16 gene alterations in the genesis of gastric carcinomas. This study aimed to detect genetic alterations of the p16 gene in gastric carcinomas. We analyzed p16 gene mutations and the frequency of loss of heterozygosity (LOH) at the p16 locus in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
