Article
Alterations of the p16/MTS1-tumor suppressor gene in gastric cancer.
Pathology, research and practice - 1 Jan 1998
Günther T, Schneider-Stock R, Pross M, Manger T, Malfertheiner P, Lippert H, Roessner A
Abstract excerpt
Deletions, mutations and the functional inactivation of tumor suppressor gene p16 are involved in the genesis of different neoplasias. Little is known about the role of p16 gene alterations in the genesis of gastric carcinomas. This study aimed to detect genetic alterations of the p16 gene in gas...
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Small Cell
- DNA, Neoplasm
- Female
- Gene Deletion
- Gene Frequency
- Genes, p16
- Humans
- Intestinal Neoplasms
- Loss of Heterozygosity
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational