Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma.

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Article

Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma.

Cancer research - 15 Jul 1995

Xiao S, Li D, Corson J M, Vijg J, Fletcher J A

Abstract excerpt

Chromosome band 9p21 is deleted frequently in non-small cell lung carcinoma (NSCLC), and the p15 and p16 cyclin-dependent kinase-4 inhibitor genes map within this deletion region. Recent studies demonstrated deletion of p15 and p16 in NSCLC metastases and cell lines, suggesting a role for these g...

Topics

Adult
Aged
Alleles
Base Sequence
Carcinoma, Non-Small-Cell Lung
Carrier Proteins
Cell Cycle Proteins
Cyclin-Dependent Kinase Inhibitor p15
Cyclin-Dependent Kinase Inhibitor p16
Female
Gene Deletion
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

In Situ Hybridization, Fluorescence

Lung Neoplasms

Male

Middle Aged

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7606711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7606711-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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