Article
Decoupling of DNA excision repair and RNA transcription in translocation breaksite regions of plasmacytoma-susceptible BALB/cAnPt mice.
Carcinogenesis - 1 Apr 1997
Beecham E J, Owens J D, Shaughnessy J D, Huppi K, Bohr V A, Mushinski J F
Abstract excerpt
Preferential repair of pyrimidine dimers in rodent cells is thought to be directly coupled to the RNA transcription machinery. The most compelling evidence for this notion is the finding that excision repair occurs more rapidly in the template strand of DNA of transcribed genes than in the non-te...
Topics
- Animals
- DNA Methylation
- DNA Repair
- Female
- Genes, myc
- Genetic Predisposition to Disease
- Mice
- Mice, Inbred BALB C
- Mice, Inbred DBA
- Plasmacytoma
- Polymorphism, Restriction Fragment Length
- RNA