Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line.

Cell - 18 Apr 1997

Bezzubova O, Silbergleit A, Yamaguchi-Iwai Y, Takeda S, Buerstedde J M

Abstract excerpt

rad54 mutants of the yeast Saccharomyces cerevisiae are extremely X-ray sensitive and have decreased mitotic recombination frequencies because of a defect in double-strand break repair. A RAD54 homolog was disrupted in the chicken B cell line DT40, which undergoes immunoglobulin gene conversion a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to B-Lymphocytes
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line

Share to Chickens

Share to Cloning, Molecular

Share to DNA, Complementary

Share to Fungal Proteins

Source

Identifiers

PMID: 9108474
DOI: 10.1016/s0092-8674(00)80198-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9108474-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line.PMID 9108474Read ↗

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs.Semantic proximity Read ↗

The 9-1-1 DNA clamp is required for immunoglobulin gene conversion.Semantic proximity Read ↗

The Rad51 paralog Rad51B promotes homologous recombinational repair.Semantic proximity Read ↗

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.Semantic proximity Read ↗

Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40.Semantic proximity Read ↗

RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells.Semantic proximity Read ↗

DNA repair: RAD alert.Semantic proximity Read ↗

Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation.Semantic proximity Read ↗

Establishment of the DNA repair-defective mutants in DT40 cells.Semantic proximity Read ↗

Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination.Semantic proximity Read ↗

Multiple roles of vertebrate REV genes in DNA repair and recombination.Semantic proximity Read ↗

The translocation activity of Rad54 reduces crossover outcomes during homologous recombinationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.