Article
ELL2, a new member of an ELL family of RNA polymerase II elongation factors.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1997
Shilatifard A, Duan D R, Haque D, Florence C, Schubach W H, Conaway J W, Conaway R C
Abstract excerpt
We recently isolated an RNA polymerase II elongation factor from rat liver nuclei and found it to be homologous to the product of the human ELL gene, a frequent target for translocations in acute myeloid leukemia. To further our understanding of the possible role(s) of ELL in transcriptional regu...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- DNA-Binding Proteins
- Genome, Human
- Humans
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins
- Peptide Elongation Factors
- Rats
- Sequence Alignment
- Transcription Factors
- Transcription Factors, General
- Transcriptional Elongation Factors