Article
The elongation factor ELL (eleven-nineteen lysine-rich leukemia) is a selective coregulator for steroid receptor functions.
Molecular endocrinology (Baltimore, Md.) - 1 May 2005
Pascual-Le Tallec Laurent, Simone Federico, Viengchareun Say, Meduri Geri, Thirman Michael J, Lombès Marc
Abstract excerpt
The dynamic and coordinated recruitment of coregulators by steroid receptors is critical for specific gene transcriptional activation. To identify new cofactors of the human (h) mineralocorticoid receptor (MR), its highly specific N-terminal domain was used as bait in a yeast two-hybrid approach. We isolated ELL (eleven-nineteen lysine-rich leukemia), a RNA polymerase II elongation factor which, when fused to MLL...
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