Article
Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import.
Journal of molecular biology - 7 Mar 1997
Percipalle P, Clarkson W D, Kent H M, Rhodes D, Stewart M
Abstract excerpt
We have used in vitro binding assays to examine specific interactions between a number of cytoplasmic and nuclear pore proteins involved in nuclear protein import in vertebrates. We demonstrate that nuclear transport factor 2 (NTF2), nucleoporin p62 and the Ras-like GTPase Ran bind to the importin heterodimer via its beta subunit. The binding behaviour of p62 truncation mutants indicated that importin-beta...
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