Article
Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import.
Journal of molecular biology - 7 Mar 1997
Percipalle P, Clarkson W D, Kent H M, Rhodes D, Stewart M
Abstract excerpt
We have used in vitro binding assays to examine specific interactions between a number of cytoplasmic and nuclear pore proteins involved in nuclear protein import in vertebrates. We demonstrate that nuclear transport factor 2 (NTF2), nucleoporin p62 and the Ras-like GTPase Ran bind to the importi...
Topics
- Amino Acid Sequence
- Animals
- Carrier Proteins
- Cell Nucleus
- DNA-Binding Proteins
- Dimerization
- Electrophoresis, Polyacrylamide Gel
- Humans
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Nuclear Envelope
