Article
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins.
Cell - 1 Dec 1995
Rexach M, Blobel G
Abstract excerpt
The molecular dynamics of nuclear protein import were examined in a solution binding assay by testing for interactions between a protein containing a nuclear localization signal (NLS), the transport factors karyopherin alpha, karyopherin beta, and Ran, and FXFG or GLFG repeat regions of nucleopor...
Topics
- Amino Acid Sequence
- Base Sequence
- Biological Transport
- Cell Nucleus
- Guanosine Triphosphate
- Humans
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Nuclear Envelope
- Nuclear Proteins
- Protein Binding
- Recombinant Fusion Proteins
- Repetitive Sequences, Nucleic Acid
- Yeasts