Article
Allelic imbalance and microsatellite instability in resected Duke's D colorectal cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Apr 1997
Kochhar R, Halling K C, McDonnell S, Schaid D J, French A J, O'Connell M J, Nagorney D M, Thibodeau S N
Abstract excerpt
Hepatic resection is the treatment of choice for selected patients with liver metastases from colorectal cancer (CRC). Although the 5-year survival rate among patients after liver resection is 25-45%, 55-75% of patients die from progressive disease. The purpose of this study was to characterize molecular genetic alterations, including microsatellite instability and allelic imbalance, in patients with potentially...
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