Article
Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers.
Journal of the National Cancer Institute - 4 Aug 1999
Halling K C, French A J, McDonnell S K, Burgart L J, Schaid D J, Peterson B J, Moon-Tasson L, Mahoney M R, Sargent D J, O'Connell M J, Witzig T E, Farr G H, Goldberg R M, Thibodeau S N
Abstract excerpt
BACKGROUND: Microsatellite instability (MSI) and allelic imbalance involving chromosome arms 5q, 8p, 17p, and 18q are genetic alterations commonly found in colorectal cancer. We investigated whether the presence or absence of these genetic alterations would allow stratification of patients with Astler-Coller stage B2 or C colorectal cancer into favorable and unfavorable prognostic groups. METHODS: Tumors from 508...
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