Article
Prognostic value of K-ras mutations and allelic imbalance on chromosome 18q in patients with resected colorectal cancer.
Diseases of the colon and rectum - 1 Apr 2001
Font A, Abad A, Monzó M, Sanchez J J, Guillot M, Manzano J L, Piñol M, Ojanguren I, Rosell R
Abstract excerpt
PURPOSE: We designed this study to assess the frequency of K-ras mutations in patients with resected colorectal tumors and their association with survival. A second objective was to analyze the prognostic value of different K-ras genotypes. In a subgroup of patients we also investigated the presence of allelic imbalance on chromosome 18q and its relationship to clinical outcome. METHODS: One hundred fourteen...
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