Article
Chromosome allele loss in colorectal liver metastases and its association with clinical features.
The British journal of surgery - 1 Jun 1994
Ding S F, Delhanty J D, Zografos G, Michail N E, Dooley J S, Habib N A
Abstract excerpt
Molecular genetic changes are better characterized in colorectal carcinoma than in other common adult tumours. Consistent allele losses, or loss of heterozygosity (LOH), on chromosomes 5q, 17p and 18q have been well established. These changes are associated with the prognosis of the disease. Little is known of such changes in liver metastases of colorectal origin. The extent of allelic loss and its association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
