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Article

Chromosome allele loss in colorectal liver metastases and its association with clinical features.

The British journal of surgery - 1 Jun 1994

Ding S F, Delhanty J D, Zografos G, Michail N E, Dooley J S, Habib N A

Abstract excerpt

Molecular genetic changes are better characterized in colorectal carcinoma than in other common adult tumours. Consistent allele losses, or loss of heterozygosity (LOH), on chromosomes 5q, 17p and 18q have been well established. These changes are associated with the prognosis of the disease. Litt...

Topics

Alleles
Blotting, Southern
Chromosome Deletion
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 5
Colorectal Neoplasms
DNA Probes
Humans
Liver Neoplasms
Lymphatic Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

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Identifiers

PMID: 8044608
DOI: 10.1002/bjs.1800810627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8044608-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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