Article
Allelic loss on chromosome 18q as a prognostic marker in stage II colorectal cancer.
Gastroenterology - 1 Jun 1998
Martínez-López E, Abad A, Font A, Monzó M, Ojanguren I, Pifarré A, Sánchez J J, Martín C, Rosell R
Abstract excerpt
BACKGROUND & AIMS: Loss of heterozygosity (LOH) on chromosome 18q is frequent in colorectal cancer (CRC) and has been associated with poor prognosis in stage II tumors. This study investigated the frequency of LOH in sporadic CRC and its effect on patient prognosis. METHODS: One hundred forty-fou...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Chromosomes, Human, Pair 18
- Colorectal Neoplasms
- Female
- Genetic Markers
- Humans
- Loss of Heterozygosity
- Male
- Microsatellite Repeats
- Middle Aged
- Multivariate Analysis
- Neoplasm Staging
- Prognosis
- Survival Analysis